Stereospecific constructions of chiral .BETA.-lactams.
نویسندگان
چکیده
منابع مشابه
Stereospecific Constructions of Chiral > Lactams
I. Amino Acids A. Alkylamino Acids: :-Alkylamino acids, L-proline, L-valine. B. Hydroxyamino Acids: L-Serine, L-threonine, D-allothreonine, L-isoserine. C. Amino-amino Acids: L-2,3-Diaminopropionic acid, L-2,4-diaminobutyric acid. D. Carboxyamino Acids: L-Aspartic acid, 3-amino-pentanedioic acids. E. Thioamino Acids: D-Penicillamine, DOr L-methylcysteine, L-cysteine, L-methionine. F. Amido-amin...
متن کاملConstructions for chiral polytopes
An abstract polytope of rank n is said to be chiral if its automorphism group has two orbits on flags, with adjacent flags lying in different orbits. In this paper, we describe a method for constructing finite chiral n-polytopes, by seeking particular normal subgroups of the orientation-preserving subgroup of n-generator Coxeter group (having the property that the subgroup is not normalized by ...
متن کاملConstructions of Chiral Polytopes of Small Rank
An abstract polytope of rank n is said to be chiral if its automorphism group has precisely two orbits on the flags, such that adjacent flags belong to distinct orbits. The present paper describes a general method for deriving new finite chiral polytopes from old finite chiral polytopes of the same rank. In particular, the technique is used to construct many new examples in ranks 3, 4 and 5.
متن کاملStereospecific pharmacokinetics and pharmacodynamics of beta-adrenergic blockers in humans.
The beta-blockers comprise a group of drugs that are mostly used to treat cardiovascular disorders such as hypertension, cardiac arrhythmia, or ischemic heart disease. Each of these drugs possesses at least one chiral center, and an inherent high degree of enantioselectivity in binding to the beta-adrenergic receptor. For beta-blockers with a single chiral center, the (-) enantiomer possesses m...
متن کاملPenetration of beta-lactams through Pseudomonas aeruginosa porin channels.
Diminished permeation of beta-lactam antibiotics in a mutant (PCC23) of Pseudomonas aeruginosa, PAO503, was investigated. Resistance to beta-lactam antibiotics could not be correlated to a change in the beta-lactamase or target proteins in strain PCC23 but was correlated with decreased permeability. In liposome swelling assays, the permeability defect was associated with strain PCC23 porin. Ami...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Journal of Antibiotics
سال: 1984
ISSN: 0021-8820,1881-1469
DOI: 10.7164/antibiotics.37.1103